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For Melanoma, Researchers Have Developed Novel Nano-Vaccine

Scientist at Tel Aviv University has developed a novel nano-vaccine for melanoma, probably the most aggressive kind of skin cancer. Their innovative method has up to now confirmed effective in stopping the event of melanoma in mouse models and in treating primary tumors and metastases that result from melanoma. The main focus of the research is on a nanoparticle that serves as the basis for the new vaccine. The examine was led by Prof. Ronit Satchi-Fainaro, chairman of the Department of Physiology and Pharmacology and the Head of Laboratory for cancer research and Nanomedicine at TAU’s Sackler Faculty of Medicine, and Prof. Helena Florindo of the University of Lisbon while on sabbatical at the Satchi-Fainaro lab at TAU; it was carried out by Dr. Anna Scomparin of Prof. Satchi-Fainaro’s TAU lab, and postdoctoral fellow Dr. João Conniot. The outcomes had been revealed on August 5 in Nature Nanotechnology. Melanoma grows in the skin cells that produce melanin or skin pigment. “The war in opposition to cancer in general, and melanoma, in particular, has superior through the years via a variety of treatment modalities, such as chemotherapy, radiation therapy, and immunotherapy; however the vaccine approach, which has confirmed so efficient against numerous viral diseases, has not materialized but against cancer,” says Prof. Satchi-Fainaro. “In our research, we’ve proven for the first time that it’s potential to provide an effective nano-vaccine against melanoma and to stimulate the immune system to immunotherapies.”

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